Virus-tumor interactome screen reveals ER stress response can reprogram resistant cancers for oncolytic virus-triggered caspase-2 cell death.

Mahoney, Douglas J

Virus-tumor interactome screen reveals ER stress response can reprogram resistant cancers for oncolytic virus-triggered caspase-2 cell death. [electronic resource] - Cancer cell Oct 2011 - 443-56 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1878-3686

10.1016/j.ccr.2011.09.005 doi


Animals
Apoptosis--physiology
Caspase 2--metabolism
Cell Line, Tumor
Cysteine Endopeptidases--metabolism
Endoplasmic Reticulum--physiology
Endoplasmic Reticulum Stress
Endoribonucleases--antagonists & inhibitors
Female
Genomics--methods
Glioblastoma--drug therapy
Humans
Mice
Mice, Nude
Oncolytic Virotherapy--methods
Oncolytic Viruses--immunology
Ovarian Neoplasms--drug therapy
Protein Serine-Threonine Kinases--antagonists & inhibitors
RNA Interference
Rhabdoviridae--physiology