CUP-5, the C. elegans ortholog of the mammalian lysosomal channel protein MLN1/TRPML1, is required for proteolytic degradation in autolysosomes.

Sun, Tao

CUP-5, the C. elegans ortholog of the mammalian lysosomal channel protein MLN1/TRPML1, is required for proteolytic degradation in autolysosomes. [electronic resource] - Autophagy Nov 2011 - 1308-15 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1554-8635

10.4161/auto.7.11.17759 doi


Alleles
Animals
Autophagy
Caenorhabditis elegans--cytology
Caenorhabditis elegans Proteins--metabolism
Embryo, Nonmammalian--metabolism
Humans
Lysosomes--metabolism
Membrane Proteins--metabolism
Mutation--genetics
Organelle Size
Protein Structure, Quaternary
Proteins--chemistry
Proteolysis
Sequence Homology, Amino Acid
Substrate Specificity
Transient Receptor Potential Channels--chemistry
Vacuoles--metabolism