Modeling human cytochrome P450 2D6 metabolism and drug-drug interaction by a novel panel of knockout and humanized mouse lines.
Scheer, Nico
Modeling human cytochrome P450 2D6 metabolism and drug-drug interaction by a novel panel of knockout and humanized mouse lines. [electronic resource] - Molecular pharmacology Jan 2012 - 63-72 p. digital
Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
1521-0111
10.1124/mol.111.075192 doi
Alleles
Animals
Cell Line
Cytochrome P-450 CYP2D6--metabolism
Drug Interactions--physiology
Embryonic Stem Cells--enzymology
Genetic Variation
Humans
Mice
Mice, Inbred BALB C
Mice, Inbred C57BL
Mice, Knockout
Mice, Transgenic
Models, Animal
Modeling human cytochrome P450 2D6 metabolism and drug-drug interaction by a novel panel of knockout and humanized mouse lines. [electronic resource] - Molecular pharmacology Jan 2012 - 63-72 p. digital
Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
1521-0111
10.1124/mol.111.075192 doi
Alleles
Animals
Cell Line
Cytochrome P-450 CYP2D6--metabolism
Drug Interactions--physiology
Embryonic Stem Cells--enzymology
Genetic Variation
Humans
Mice
Mice, Inbred BALB C
Mice, Inbred C57BL
Mice, Knockout
Mice, Transgenic
Models, Animal