Thiocolchicoside suppresses osteoclastogenesis induced by RANKL and cancer cells through inhibition of inflammatory pathways: a new use for an old drug.

Reuter, Simone

Thiocolchicoside suppresses osteoclastogenesis induced by RANKL and cancer cells through inhibition of inflammatory pathways: a new use for an old drug. [electronic resource] - British journal of pharmacology Apr 2012 - 2127-39 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1476-5381

10.1111/j.1476-5381.2011.01702.x doi


Animals
Bone Neoplasms--drug therapy
Bone Resorption--drug therapy
Cell Line
Colchicine--analogs & derivatives
Enzyme Activation--drug effects
Female
Humans
I-kappa B Kinase--metabolism
Inflammation--prevention & control
Liliaceae--chemistry
Male
Mice
NF-kappa B--metabolism
Osteoclasts--drug effects
Phytotherapy
RANK Ligand--physiology
Signal Transduction--drug effects