Intrinsic sexually dimorphic expression of the principal human CYP3A4 correlated with suboptimal activation of GH/glucocorticoid-dependent transcriptional pathways in men.

Thangavel, Chellappagounder

Intrinsic sexually dimorphic expression of the principal human CYP3A4 correlated with suboptimal activation of GH/glucocorticoid-dependent transcriptional pathways in men. [electronic resource] - Endocrinology Dec 2011 - 4813-24 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1945-7170

10.1210/en.2011-1274 doi


Biological Transport
Cells, Cultured
Cytochrome P-450 CYP3A--genetics
Dexamethasone--pharmacology
Glucocorticoids--metabolism
Growth Hormone--metabolism
Hepatocyte Nuclear Factor 4
Hepatocytes
Human Growth Hormone--pharmacology
Humans
Male
Sex Characteristics
Sex Factors
Transcription Factors--metabolism
Transcription, Genetic