Phosphodiesterase 4 inhibition attenuates persistent heart and lung injury by neonatal hyperoxia in rats.

de Visser, Yvonne P

Phosphodiesterase 4 inhibition attenuates persistent heart and lung injury by neonatal hyperoxia in rats. [electronic resource] - American journal of physiology. Lung cellular and molecular physiology Jan 2012 - L56-67 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural

1522-1504

10.1152/ajplung.00041.2011 doi


Animals
Animals, Newborn
Benzamides--pharmacology
Bronchopulmonary Dysplasia--drug therapy
Cyclic Nucleotide Phosphodiesterases, Type 4--metabolism
Disease Models, Animal
Heart--drug effects
Heart Injuries--drug therapy
Humans
Hyperoxia--drug therapy
Hypertension, Pulmonary--drug therapy
Hypertrophy, Right Ventricular--drug therapy
Infant, Newborn
Lung--drug effects
Oxidative Stress--drug effects
Oxygen--pharmacology
Phosphodiesterase 4 Inhibitors--pharmacology
Pulmonary Alveoli--drug effects
Pyridines--pharmacology
Rats