ALK mutations conferring differential resistance to structurally diverse ALK inhibitors.
Heuckmann, Johannes M
ALK mutations conferring differential resistance to structurally diverse ALK inhibitors. [electronic resource] - Clinical cancer research : an official journal of the American Association for Cancer Research Dec 2011 - 7394-401 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
1557-3265
10.1158/1078-0432.CCR-11-1648 doi
Anaplastic Lymphoma Kinase
Antineoplastic Agents--pharmacology
Cell Cycle Proteins--genetics
Cell Line, Tumor
Crizotinib
Drug Resistance, Neoplasm--genetics
Humans
Lung Neoplasms--drug therapy
Microtubule-Associated Proteins--genetics
Mutation
Neuroblastoma--drug therapy
Oncogene Proteins, Fusion--genetics
Polymorphism, Single Nucleotide
Pyrazoles--pharmacology
Pyridines--pharmacology
Pyrimidines--pharmacology
Receptor Protein-Tyrosine Kinases--antagonists & inhibitors
Serine Endopeptidases--genetics
ALK mutations conferring differential resistance to structurally diverse ALK inhibitors. [electronic resource] - Clinical cancer research : an official journal of the American Association for Cancer Research Dec 2011 - 7394-401 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
1557-3265
10.1158/1078-0432.CCR-11-1648 doi
Anaplastic Lymphoma Kinase
Antineoplastic Agents--pharmacology
Cell Cycle Proteins--genetics
Cell Line, Tumor
Crizotinib
Drug Resistance, Neoplasm--genetics
Humans
Lung Neoplasms--drug therapy
Microtubule-Associated Proteins--genetics
Mutation
Neuroblastoma--drug therapy
Oncogene Proteins, Fusion--genetics
Polymorphism, Single Nucleotide
Pyrazoles--pharmacology
Pyridines--pharmacology
Pyrimidines--pharmacology
Receptor Protein-Tyrosine Kinases--antagonists & inhibitors
Serine Endopeptidases--genetics