Stereoselective pharmacokinetics of stable isotope (+/-)-[13C]-pantoprazole: Implications for a rapid screening phenotype test of CYP2C19 activity.

Thacker, David L

Stereoselective pharmacokinetics of stable isotope (+/-)-[13C]-pantoprazole: Implications for a rapid screening phenotype test of CYP2C19 activity. [electronic resource] - Chirality Nov 2011 - 904-9 p. digital

Publication Type: Clinical Trial; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1520-636X

10.1002/chir.21011 doi


2-Pyridinylmethylsulfinylbenzimidazoles--chemistry
Adolescent
Adult
Breath Tests
Carbon Isotopes--chemistry
Cytochrome P-450 CYP2C19--metabolism
Enzyme Assays--methods
Female
Humans
Male
Middle Aged
Pantoprazole
Phenotype
Stereoisomerism
Substrate Specificity
Young Adult