Double knockdown of prolyl hydroxylase and factor-inhibiting hypoxia-inducible factor with nonviral minicircle gene therapy enhances stem cell mobilization and angiogenesis after myocardial infarction.

Huang, Mei

Double knockdown of prolyl hydroxylase and factor-inhibiting hypoxia-inducible factor with nonviral minicircle gene therapy enhances stem cell mobilization and angiogenesis after myocardial infarction. [electronic resource] - Circulation Sep 2011 - S46-54 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1524-4539

10.1161/CIRCULATIONAHA.110.014019 doi


Animals
Apoptosis--physiology
Embryonic Stem Cells--cytology
Female
Gene Knockdown Techniques
Genetic Therapy--methods
Hypoxia-Inducible Factor 1, alpha Subunit--metabolism
Mice
Mice, Inbred Strains
Mixed Function Oxygenases--genetics
Models, Animal
Myoblasts, Cardiac--metabolism
Myocardial Infarction--metabolism
Myocardium--metabolism
Myocytes, Cardiac--metabolism
Neovascularization, Physiologic--physiology
Procollagen-Proline Dioxygenase--genetics
Stem Cell Transplantation
Treatment Outcome