Inhibition of Gsk3β in cartilage induces osteoarthritic features through activation of the canonical Wnt signaling pathway.

Miclea, R L

Inhibition of Gsk3β in cartilage induces osteoarthritic features through activation of the canonical Wnt signaling pathway. [electronic resource] - Osteoarthritis and cartilage Nov 2011 - 1363-72 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1522-9653

10.1016/j.joca.2011.07.014 doi


Animals
Biomarkers--metabolism
Cartilage, Articular--metabolism
Chondrocytes--metabolism
Extracellular Matrix--metabolism
Glycogen Synthase Kinase 3--antagonists & inhibitors
Glycogen Synthase Kinase 3 beta
Glycosaminoglycans--metabolism
Hindlimb
Mice
Peptide Hydrolases--metabolism
Protein Array Analysis
Rats
Wnt Signaling Pathway--drug effects
beta Catenin--metabolism