K201 (JTV-519) alters the spatiotemporal properties of diastolic Ca(2+) release and the associated diastolic contraction during β-adrenergic stimulation in rat ventricular cardiomyocytes.

Elliott, E B

K201 (JTV-519) alters the spatiotemporal properties of diastolic Ca(2+) release and the associated diastolic contraction during β-adrenergic stimulation in rat ventricular cardiomyocytes. [electronic resource] - Basic research in cardiology Nov 2011 - 1009-22 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1435-1803

10.1007/s00395-011-0218-4 doi


Action Potentials--drug effects
Animals
Calcium--metabolism
Diastole--drug effects
Heart Ventricles--drug effects
Male
Microscopy, Confocal
Myocardial Contraction--drug effects
Myocytes, Cardiac--drug effects
Patch-Clamp Techniques
Rats
Rats, Wistar
Sarcoplasmic Reticulum--drug effects
Thiazepines--pharmacology