Mediobasal hypothalamic SIRT1 is essential for resveratrol's effects on insulin action in rats.

Knight, Colette M

Mediobasal hypothalamic SIRT1 is essential for resveratrol's effects on insulin action in rats. [electronic resource] - Diabetes 11 2011 - 2691-700 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural

1939-327X

10.2337/db10-0987 doi


Animals
Enzyme Activators--administration & dosage
Enzyme Inhibitors--administration & dosage
Gene Silencing
Glucose--metabolism
Hypoglycemic Agents--pharmacology
Hypothalamus, Middle--drug effects
Insulin--pharmacology
Insulin Antagonists--pharmacology
Insulin Resistance
KATP Channels--antagonists & inhibitors
Liver--drug effects
Male
Organ Specificity
Potassium Channel Blockers--pharmacology
RNA, Small Interfering
Rats
Rats, Sprague-Dawley
Resveratrol
Sirtuin 1--antagonists & inhibitors
Stilbenes--administration & dosage