Synthesis and SAR optimization of diketo acid pharmacophore for HCV NS5B polymerase inhibition.
Bhatt, Aaditya
Synthesis and SAR optimization of diketo acid pharmacophore for HCV NS5B polymerase inhibition. [electronic resource] - European journal of medicinal chemistry Oct 2011 - 5138-45 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
1768-3254
10.1016/j.ejmech.2011.08.028 doi
Acids--chemical synthesis
Antiviral Agents--chemical synthesis
Hepacivirus--drug effects
Hepatitis C--drug therapy
Humans
Models, Molecular
Protein Binding
RNA-Dependent RNA Polymerase--antagonists & inhibitors
Structure-Activity Relationship
Viral Nonstructural Proteins--antagonists & inhibitors
Synthesis and SAR optimization of diketo acid pharmacophore for HCV NS5B polymerase inhibition. [electronic resource] - European journal of medicinal chemistry Oct 2011 - 5138-45 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
1768-3254
10.1016/j.ejmech.2011.08.028 doi
Acids--chemical synthesis
Antiviral Agents--chemical synthesis
Hepacivirus--drug effects
Hepatitis C--drug therapy
Humans
Models, Molecular
Protein Binding
RNA-Dependent RNA Polymerase--antagonists & inhibitors
Structure-Activity Relationship
Viral Nonstructural Proteins--antagonists & inhibitors