A NOTCH3-mediated squamous cell differentiation program limits expansion of EMT-competent cells that express the ZEB transcription factors.

Ohashi, Shinya

A NOTCH3-mediated squamous cell differentiation program limits expansion of EMT-competent cells that express the ZEB transcription factors. [electronic resource] - Cancer research Nov 2011 - 6836-47 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1538-7445

10.1158/0008-5472.CAN-11-0846 doi


Animals
Antigens, CD
Cadherins--biosynthesis
Carcinoma, Squamous Cell--genetics
Cell Division
Cell Line, Tumor
DNA-Binding Proteins--physiology
Epithelial-Mesenchymal Transition--genetics
Esophageal Neoplasms--genetics
Gene Expression Regulation, Neoplastic
Homeodomain Proteins--physiology
Humans
Mice
Mice, Nude
MicroRNAs--biosynthesis
Neoplasm Proteins--biosynthesis
Neoplasm Transplantation
RNA Interference
RNA, Neoplasm--biosynthesis
RNA, Small Interfering--pharmacology
Receptor, Notch3
Receptors, Notch--physiology
Recombinant Fusion Proteins--physiology
Repressor Proteins--physiology
Signal Transduction
Transcription Factors--physiology
Tumor Stem Cell Assay
Zinc Finger E-box Binding Homeobox 2
Zinc Finger E-box-Binding Homeobox 1