A pilot study of poly(N-isopropylacrylamide)-g-polyethylene glycol and poly(N-isopropylacrylamide)-g-methylcellulose branched copolymers as injectable scaffolds for local delivery of neurotrophins and cellular transplants into the injured spinal cord.

Conova, Lauren

A pilot study of poly(N-isopropylacrylamide)-g-polyethylene glycol and poly(N-isopropylacrylamide)-g-methylcellulose branched copolymers as injectable scaffolds for local delivery of neurotrophins and cellular transplants into the injured spinal cord. [electronic resource] - Journal of neurosurgery. Spine Dec 2011 - 594-604 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.

1547-5646

10.3171/2011.7.SPINE11194 doi


Acrylamides--pharmacology
Acrylic Resins
Animals
Axons--drug effects
Brain-Derived Neurotrophic Factor--pharmacology
Cell Transplantation--methods
Cicatrix--physiopathology
Disease Models, Animal
Drug Delivery Systems--methods
Female
Graft Survival--physiology
Hydrogels--pharmacology
Injections, Intralesional
Methylcellulose--pharmacology
Nerve Regeneration--drug effects
Neuroglia--drug effects
Pilot Projects
Polyethylene Glycols--pharmacology
Polymers--pharmacology
Rats
Rats, Sprague-Dawley
Spinal Cord Injuries--therapy
Tissue Scaffolds