Structure of human SMYD2 protein reveals the basis of p53 tumor suppressor methylation.

Wang, Li

Structure of human SMYD2 protein reveals the basis of p53 tumor suppressor methylation. [electronic resource] - The Journal of biological chemistry Nov 2011 - 38725-38737 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1083-351X

10.1074/jbc.M111.262410 doi


Calorimetry--methods
Cell Line, Tumor
Crystallography, X-Ray--methods
Genes, Tumor Suppressor
Histone-Lysine N-Methyltransferase--chemistry
Histones--chemistry
Humans
Kinetics
Lysine--chemistry
Methylation
Molecular Conformation
Neoplasms--metabolism
Protein Binding
Transcription, Genetic
Tumor Suppressor Protein p53--chemistry