Enhanced bioavailability of atorvastatin calcium from stabilized gastric resident formulation.

Khan, Furquan Nazimuddin

Enhanced bioavailability of atorvastatin calcium from stabilized gastric resident formulation. [electronic resource] - AAPS PharmSciTech Dec 2011 - 1077-86 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1530-9932

10.1208/s12249-011-9673-3 doi


Administration, Oral
Animals
Atorvastatin
Biological Availability
Calorimetry, Differential Scanning
Carboxymethylcellulose Sodium--chemistry
Chemistry, Pharmaceutical
Delayed-Action Preparations
Dioctyl Sulfosuccinic Acid--chemistry
Drug Compounding
Drug Stability
Excipients--chemistry
Female
Gastric Mucosa--metabolism
Heptanoic Acids--administration & dosage
Hydroxymethylglutaryl-CoA Reductase Inhibitors--administration & dosage
Hypromellose Derivatives
Male
Mannitol--chemistry
Methylcellulose--analogs & derivatives
Polyethylene Glycols--chemistry
Powder Diffraction
Pyrroles--administration & dosage
Rabbits
Regression Analysis
Sodium Bicarbonate--chemistry
Solubility
Stearic Acids--chemistry
Tablets
Technology, Pharmaceutical--methods
Viscosity
Water--chemistry
X-Ray Diffraction