Indole-3-carbinol enhances the resolution of rat liver fibrosis and stimulates hepatic stellate cell apoptosis by blocking the inhibitor of κB kinase α/inhibitor of κB-α/nuclear factor-κB pathway.

Ping, Jie

Indole-3-carbinol enhances the resolution of rat liver fibrosis and stimulates hepatic stellate cell apoptosis by blocking the inhibitor of κB kinase α/inhibitor of κB-α/nuclear factor-κB pathway. [electronic resource] - The Journal of pharmacology and experimental therapeutics Nov 2011 - 694-703 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Retracted Publication

1521-0103

10.1124/jpet.111.179820 doi


Animals
Apoptosis--drug effects
Bile Ducts--pathology
Carbon Tetrachloride--toxicity
Curcumin--pharmacology
Electrophoretic Mobility Shift Assay
Enzyme Inhibitors--pharmacology
Hepatic Stellate Cells--drug effects
I-kappa B Kinase--metabolism
I-kappa B Proteins--metabolism
Indoles--pharmacology
Liver--drug effects
Liver Cirrhosis--drug therapy
Male
NF-KappaB Inhibitor alpha
NF-kappa B--metabolism
Phosphorylation
Protein Array Analysis
Rats
Rats, Wistar
Signal Transduction--drug effects
Solvents
Swine--blood
Transfection