β-Catenin signaling increases during melanoma progression and promotes tumor cell survival and chemoresistance.

Sinnberg, Tobias

β-Catenin signaling increases during melanoma progression and promotes tumor cell survival and chemoresistance. [electronic resource] - PloS one 2011 - e23429 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1932-6203

10.1371/journal.pone.0023429 doi


Animals
Antineoplastic Agents--pharmacology
Cell Line, Tumor
Cell Movement--drug effects
Cell Proliferation--drug effects
Cells, Cultured
Cisplatin--pharmacology
Dose-Response Relationship, Drug
Doxycycline--pharmacology
Drug Synergism
HCT116 Cells
Humans
Male
Melanocytes--cytology
Melanoma--genetics
Melanoma, Experimental--genetics
Mice
Mice, SCID
Perylene--analogs & derivatives
RNA Interference
Signal Transduction
TCF Transcription Factors--antagonists & inhibitors
Tumor Burden--drug effects
Xenograft Model Antitumor Assays
beta Catenin--antagonists & inhibitors