Evaluation of submicron emulsion as vehicles for rapid-onset intranasal delivery and improvement in brain targeting of zolmitriptan.

Yu, Chaoqun

Evaluation of submicron emulsion as vehicles for rapid-onset intranasal delivery and improvement in brain targeting of zolmitriptan. [electronic resource] - Drug delivery Nov 2011 - 578-85 p. digital

Publication Type: Evaluation Study; Journal Article

1521-0464

10.3109/10717544.2011.600784 doi


Administration, Intranasal
Amines--chemistry
Animals
Area Under Curve
Biological Availability
Brain--metabolism
Cerebral Ventricles--metabolism
Drug Delivery Systems--methods
Emulsions
Glycerol--chemistry
Injections, Intravenous
Lecithins--chemistry
Oleic Acid--chemistry
Oxazolidinones--administration & dosage
Particle Size
Pharmaceutical Vehicles--chemistry
Poloxamer--chemistry
Rats
Rats, Wistar
Serotonin 5-HT1 Receptor Agonists--administration & dosage
Solubility
Static Electricity
Triglycerides--chemistry
Tryptamines--administration & dosage