Bone fragility and decline in stem cells in prematurely aging DNA repair deficient trichothiodystrophy mice.

Diderich, Karin E M

Bone fragility and decline in stem cells in prematurely aging DNA repair deficient trichothiodystrophy mice. [electronic resource] - Age (Dordrecht, Netherlands) Aug 2012 - 845-61 p. digital

Publication Type: Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1574-4647

10.1007/s11357-011-9291-8 doi


Age Factors
Aging, Premature--genetics
Analysis of Variance
Animals
Bone and Bones--drug effects
DNA Damage--drug effects
DNA Repair-Deficiency Disorders--genetics
Disease Models, Animal
Female
Hematopoietic Stem Cells--metabolism
Immunohistochemistry
Mice
Mice, Inbred C57BL
Microscopy, Electron
Osteoblasts--metabolism
Osteoclasts--metabolism
Osteogenesis--drug effects
Osteoporosis--genetics
Parathyroid Hormone--pharmacology
Random Allocation
Reference Values
Sensitivity and Specificity
Trichothiodystrophy Syndromes--genetics