The use of a gold nanoparticle-based adjuvant to improve the therapeutic efficacy of hNgR-Fc protein immunization in spinal cord-injured rats.

Wang, Yong-Tang

The use of a gold nanoparticle-based adjuvant to improve the therapeutic efficacy of hNgR-Fc protein immunization in spinal cord-injured rats. [electronic resource] - Biomaterials Nov 2011 - 7988-98 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1878-5905

10.1016/j.biomaterials.2011.07.009 doi


Adjuvants, Immunologic--therapeutic use
Animals
Axons--drug effects
GAP-43 Protein--metabolism
GPI-Linked Proteins--immunology
Gold--therapeutic use
Humans
Immune Sera--immunology
Immunization
Metal Nanoparticles--therapeutic use
Myelin Proteins--immunology
Nerve Regeneration--drug effects
Neurites--drug effects
Neuroprotective Agents--pharmacology
Nogo Receptor 1
Rats
Receptors, Cell Surface--immunology
Receptors, Fc--immunology
Recombinant Fusion Proteins--immunology
Recovery of Function--drug effects
Spinal Cord--drug effects
Spinal Cord Injuries--immunology
Treatment Outcome
Vaccines--immunology
Wound Healing--drug effects