The protective effects of ascorbic acid, cimetidine, and nifedipine on diethyldithiocarbamate-induced hepatic toxicity in albino rats.

Gaafa, Khadiga Mohammed

The protective effects of ascorbic acid, cimetidine, and nifedipine on diethyldithiocarbamate-induced hepatic toxicity in albino rats. [electronic resource] - Drug and chemical toxicology Oct 2011 - 405-19 p. digital

Publication Type: Journal Article

1525-6014

10.3109/01480545.2011.586035 doi


Animals
Ascorbic Acid--administration & dosage
Biomarkers--analysis
Calcium--metabolism
Chemical and Drug Induced Liver Injury--etiology
Cimetidine--administration & dosage
Cytochrome P-450 Enzyme System--metabolism
Ditiocarb--toxicity
Dose-Response Relationship, Drug
Glutathione--metabolism
Lipid Peroxidation--drug effects
Liver--drug effects
Male
Malondialdehyde--metabolism
Nifedipine--administration & dosage
Oxidative Stress--drug effects
Protective Agents--administration & dosage
Rats
Rats, Sprague-Dawley
Superoxide Dismutase--metabolism
Time Factors