cAMP-secretion coupling is impaired in diabetic GK/Par rat β-cells: a defect counteracted by GLP-1.

Dolz, Manuel

cAMP-secretion coupling is impaired in diabetic GK/Par rat β-cells: a defect counteracted by GLP-1. [electronic resource] - American journal of physiology. Endocrinology and metabolism Nov 2011 - E797-806 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1522-1555

10.1152/ajpendo.00652.2010 doi


Animals
Cells, Cultured
Cyclic AMP--metabolism
Diabetes Mellitus, Experimental--chemically induced
Diabetes Mellitus, Type 2--chemically induced
Disease Models, Animal
Glucagon-Like Peptide 1--pharmacology
Glucose--pharmacology
Insulin--metabolism
Insulin Secretion
Insulin-Secreting Cells--drug effects
Male
Rats
Rats, Wistar
Secretory Pathway--drug effects
Streptozocin