Antitumor activity of a recombinant soluble ectodomain of mutant human fibroblast growth factor receptor-2 IIIc.
Wang, Ju
Antitumor activity of a recombinant soluble ectodomain of mutant human fibroblast growth factor receptor-2 IIIc. [electronic resource] - Molecular cancer therapeutics Sep 2011 - 1656-66 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1538-8514
10.1158/1535-7163.MCT-11-0163 doi
Animals
Antineoplastic Agents--pharmacology
Apoptosis--drug effects
Cell Line, Transformed
Cell Line, Tumor
Cell Proliferation--drug effects
Female
Humans
Kaplan-Meier Estimate
Ligands
Mice
Mice, Inbred BALB C
Mice, Nude
Mutant Proteins--genetics
NIH 3T3 Cells
Neoplasm Metastasis--drug therapy
Neoplasms--drug therapy
Neovascularization, Physiologic--drug effects
Peptide Fragments--chemistry
Protein Binding
Receptor, Fibroblast Growth Factor, Type 2--chemistry
Recombinant Proteins--chemistry
Signal Transduction--drug effects
Tumor Burden--drug effects
Xenograft Model Antitumor Assays
Antitumor activity of a recombinant soluble ectodomain of mutant human fibroblast growth factor receptor-2 IIIc. [electronic resource] - Molecular cancer therapeutics Sep 2011 - 1656-66 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1538-8514
10.1158/1535-7163.MCT-11-0163 doi
Animals
Antineoplastic Agents--pharmacology
Apoptosis--drug effects
Cell Line, Transformed
Cell Line, Tumor
Cell Proliferation--drug effects
Female
Humans
Kaplan-Meier Estimate
Ligands
Mice
Mice, Inbred BALB C
Mice, Nude
Mutant Proteins--genetics
NIH 3T3 Cells
Neoplasm Metastasis--drug therapy
Neoplasms--drug therapy
Neovascularization, Physiologic--drug effects
Peptide Fragments--chemistry
Protein Binding
Receptor, Fibroblast Growth Factor, Type 2--chemistry
Recombinant Proteins--chemistry
Signal Transduction--drug effects
Tumor Burden--drug effects
Xenograft Model Antitumor Assays