Transactivation of epidermal growth factor receptor by enhanced levels of endogenous angiotensin II contributes to the overexpression of Giα proteins in vascular smooth muscle cells from SHR.

Sandoval, Yessica-Haydee Gomez

Transactivation of epidermal growth factor receptor by enhanced levels of endogenous angiotensin II contributes to the overexpression of Giα proteins in vascular smooth muscle cells from SHR. [electronic resource] - Cellular signalling Nov 2011 - 1716-26 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1873-3913

10.1016/j.cellsig.2011.06.006 doi


Acetylcysteine--pharmacology
Adenylyl Cyclases--metabolism
Angiotensin II--genetics
Angiotensin-Converting Enzyme Inhibitors--pharmacology
Animals
CSK Tyrosine-Protein Kinase
Colforsin--pharmacology
ErbB Receptors--genetics
GTP-Binding Protein alpha Subunits, Gi-Go--genetics
Gene Expression--drug effects
Guanosine 5'-O-(3-Thiotriphosphate)--pharmacology
Humans
Hypertension--genetics
Mitogen-Activated Protein Kinases--genetics
Muscle, Smooth, Vascular--cytology
Myocytes, Smooth Muscle--cytology
Oxidative Stress--drug effects
Phosphorylation
Protein-Tyrosine Kinases--genetics
Rats
Rats, Inbred SHR
Rats, Inbred WKY
Signal Transduction--drug effects
Transcriptional Activation--drug effects
src-Family Kinases