Structural alert/reactive metabolite concept as applied in medicinal chemistry to mitigate the risk of idiosyncratic drug toxicity: a perspective based on the critical examination of trends in the top 200 drugs marketed in the United States.
Stepan, Antonia F
Structural alert/reactive metabolite concept as applied in medicinal chemistry to mitigate the risk of idiosyncratic drug toxicity: a perspective based on the critical examination of trends in the top 200 drugs marketed in the United States. [electronic resource] - Chemical research in toxicology Sep 2011 - 1345-410 p. digital
Publication Type: Journal Article; Review
1520-5010
10.1021/tx200168d doi
Animals
Drug Discovery--methods
Drug Recalls
Drug-Related Side Effects and Adverse Reactions--epidemiology
Humans
Pharmaceutical Preparations--chemistry
United States--epidemiology
Structural alert/reactive metabolite concept as applied in medicinal chemistry to mitigate the risk of idiosyncratic drug toxicity: a perspective based on the critical examination of trends in the top 200 drugs marketed in the United States. [electronic resource] - Chemical research in toxicology Sep 2011 - 1345-410 p. digital
Publication Type: Journal Article; Review
1520-5010
10.1021/tx200168d doi
Animals
Drug Discovery--methods
Drug Recalls
Drug-Related Side Effects and Adverse Reactions--epidemiology
Humans
Pharmaceutical Preparations--chemistry
United States--epidemiology