Synthesis of novel inhibitors of β-glucuronidase based on benzothiazole skeleton and study of their binding affinity by molecular docking.

Khan, Khalid Mohammed

Synthesis of novel inhibitors of β-glucuronidase based on benzothiazole skeleton and study of their binding affinity by molecular docking. [electronic resource] - Bioorganic & medicinal chemistry Jul 2011 - 4286-94 p. digital

Publication Type: Journal Article

1464-3391

10.1016/j.bmc.2011.05.052 doi


Animals
Benzothiazoles--chemical synthesis
Binding Sites--drug effects
Cattle
Crystallography, X-Ray
Glucuronidase--antagonists & inhibitors
Glycoproteins--chemical synthesis
Humans
Liver--enzymology
Models, Molecular
Molecular Structure
Stereoisomerism
Structure-Activity Relationship