The tryptophan hydroxylase inhibitor LX1031 shows clinical benefit in patients with nonconstipating irritable bowel syndrome.

Brown, Philip M

The tryptophan hydroxylase inhibitor LX1031 shows clinical benefit in patients with nonconstipating irritable bowel syndrome. [electronic resource] - Gastroenterology Aug 2011 - 507-16 p. digital

Publication Type: Clinical Trial, Phase II; Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't

1528-0012

10.1053/j.gastro.2011.05.005 doi


Abdominal Pain--etiology
Adult
Biomarkers--urine
Biphenyl Compounds--administration & dosage
Constipation
Double-Blind Method
Feces
Female
Humans
Hydroxyindoleacetic Acid--urine
Irritable Bowel Syndrome--complications
Male
Middle Aged
Pain Measurement
Phenylalanine--administration & dosage
Serotonin--biosynthesis
Severity of Illness Index
Tryptophan Hydroxylase--antagonists & inhibitors