ERK pathway mediates P2X7 expression and cell death in renal interstitial fibroblasts exposed to necrotic renal epithelial cells.
Ponnusamy, Murugavel
ERK pathway mediates P2X7 expression and cell death in renal interstitial fibroblasts exposed to necrotic renal epithelial cells. [electronic resource] - American journal of physiology. Renal physiology Sep 2011 - F650-9 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural
1522-1466
10.1152/ajprenal.00215.2011 doi
Animals
Apoptosis--physiology
Cell Communication--physiology
Cell Line
Epithelial Cells--metabolism
Extracellular Signal-Regulated MAP Kinases--metabolism
Fibroblasts--metabolism
Kidney Cortex Necrosis--metabolism
Kidney Tubules, Proximal--metabolism
MAP Kinase Kinase 1--antagonists & inhibitors
MAP Kinase Kinase 4--metabolism
Mice
Models, Animal
Proto-Oncogene Proteins c-akt--metabolism
RNA, Small Interfering--pharmacology
Rats
Receptors, Purinergic P2X7--drug effects
Signal Transduction--physiology
ets-Domain Protein Elk-1--metabolism
p38 Mitogen-Activated Protein Kinases--metabolism
ERK pathway mediates P2X7 expression and cell death in renal interstitial fibroblasts exposed to necrotic renal epithelial cells. [electronic resource] - American journal of physiology. Renal physiology Sep 2011 - F650-9 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural
1522-1466
10.1152/ajprenal.00215.2011 doi
Animals
Apoptosis--physiology
Cell Communication--physiology
Cell Line
Epithelial Cells--metabolism
Extracellular Signal-Regulated MAP Kinases--metabolism
Fibroblasts--metabolism
Kidney Cortex Necrosis--metabolism
Kidney Tubules, Proximal--metabolism
MAP Kinase Kinase 1--antagonists & inhibitors
MAP Kinase Kinase 4--metabolism
Mice
Models, Animal
Proto-Oncogene Proteins c-akt--metabolism
RNA, Small Interfering--pharmacology
Rats
Receptors, Purinergic P2X7--drug effects
Signal Transduction--physiology
ets-Domain Protein Elk-1--metabolism
p38 Mitogen-Activated Protein Kinases--metabolism