Inhibition of miR-193a expression by Max and RXRα activates K-Ras and PLAU to mediate distinct aspects of cellular transformation.

Iliopoulos, Dimitrios

Inhibition of miR-193a expression by Max and RXRα activates K-Ras and PLAU to mediate distinct aspects of cellular transformation. [electronic resource] - Cancer research Aug 2011 - 5144-53 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural

1538-7445

10.1158/0008-5472.CAN-11-0425 doi


3' Untranslated Regions--genetics
Animals
Basic Helix-Loop-Helix Leucine Zipper Transcription Factors--genetics
Breast--cytology
Cell Line--metabolism
Cell Line, Tumor--metabolism
Cell Transformation, Neoplastic--genetics
Chromatin Immunoprecipitation
Epithelial Cells--cytology
Fibroblasts--cytology
Gene Expression Profiling
Gene Expression Regulation, Neoplastic--drug effects
Genes, ras
Genes, src
Humans
Mice
Mice, Nude
MicroRNAs--biosynthesis
Neoplasm Invasiveness--genetics
Neoplasm Proteins--physiology
RNA, Small Interfering--pharmacology
Random Allocation
Retinoid X Receptor alpha
Tumor Stem Cell Assay
Urokinase-Type Plasminogen Activator--physiology