Nomilin inhibits metastasis via induction of apoptosis and regulates the activation of transcription factors and the cytokine profile in B16F-10 cells.

Pratheeshkumar, Poyil

Nomilin inhibits metastasis via induction of apoptosis and regulates the activation of transcription factors and the cytokine profile in B16F-10 cells. [electronic resource] - Integrative cancer therapies Mar 2012 - 48-60 p. digital

Publication Type: Journal Article

1552-695X

10.1177/1534735411403307 doi


Activating Transcription Factor 2--genetics
Animals
Antineoplastic Agents, Phytogenic--pharmacology
Apoptosis--drug effects
Benzoxepins--pharmacology
Caspase 3--genetics
Caspase 9--genetics
Cell Cycle--drug effects
Cell Line, Tumor
Cyclic AMP Response Element-Binding Protein--genetics
Cyclin D1--genetics
Cyclin-Dependent Kinase Inhibitor p21--genetics
Cyclin-Dependent Kinase Inhibitor p27--genetics
DNA Fragmentation--drug effects
Down-Regulation--drug effects
Limonins--pharmacology
Lung Neoplasms--drug therapy
Male
Matrix Metalloproteinase Inhibitors
Matrix Metalloproteinases--genetics
Melanoma, Experimental--drug therapy
Mice
Mice, Inbred C57BL
NF-kappa B--genetics
Neoplasm Invasiveness--genetics
Neoplasm Metastasis
Plant Extracts--pharmacology
Proto-Oncogene Proteins c-bcl-2--genetics
Survival Rate
Transcription Factors--genetics
Tumor Suppressor Protein p53--genetics
Up-Regulation--drug effects
bcl-2-Associated X Protein--genetics