Diminishing returns epistasis among beneficial mutations decelerates adaptation.

Chou, Hsin-Hung

Diminishing returns epistasis among beneficial mutations decelerates adaptation. [electronic resource] - Science (New York, N.Y.) Jun 2011 - 1190-2 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.

1095-9203

10.1126/science.1203799 doi


Adaptation, Physiological
Alleles
Biological Evolution
Epistasis, Genetic
Evolution, Molecular
Genes, Bacterial
Genetic Fitness
Genome, Bacterial
Glutathione--metabolism
Metabolic Networks and Pathways--genetics
Methylobacterium extorquens--cytology
Models, Genetic
Mutation
Selection, Genetic