Quantitative prediction of human pregnane X receptor and cytochrome P450 3A4 mediated drug-drug interaction in a novel multiple humanized mouse line.
Hasegawa, Maki
Quantitative prediction of human pregnane X receptor and cytochrome P450 3A4 mediated drug-drug interaction in a novel multiple humanized mouse line. [electronic resource] - Molecular pharmacology Sep 2011 - 518-28 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1521-0111
10.1124/mol.111.071845 doi
Animals
Cytochrome P-450 CYP3A--drug effects
Drug Interactions
Humans
Mice
Mice, Inbred C57BL
Mice, Transgenic
Pregnane X Receptor
Receptors, Steroid--drug effects
Quantitative prediction of human pregnane X receptor and cytochrome P450 3A4 mediated drug-drug interaction in a novel multiple humanized mouse line. [electronic resource] - Molecular pharmacology Sep 2011 - 518-28 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1521-0111
10.1124/mol.111.071845 doi
Animals
Cytochrome P-450 CYP3A--drug effects
Drug Interactions
Humans
Mice
Mice, Inbred C57BL
Mice, Transgenic
Pregnane X Receptor
Receptors, Steroid--drug effects