Rapid pyrophosphate release from transcriptional elongation complexes appears to be coupled to a nucleotide-induced conformational change in E. coli core polymerase.

Johnson, Ronald S

Rapid pyrophosphate release from transcriptional elongation complexes appears to be coupled to a nucleotide-induced conformational change in E. coli core polymerase. [electronic resource] - Journal of molecular biology Oct 2011 - 849-61 p. digital

Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.

1089-8638

10.1016/j.jmb.2011.05.023 doi


DNA-Directed RNA Polymerases--metabolism
Diphosphates--metabolism
Escherichia coli--enzymology
Kinetics
Nucleotides--metabolism
Protein Conformation
Transcription, Genetic