Suramin inhibits renal fibrosis in chronic kidney disease.

Liu, Na

Suramin inhibits renal fibrosis in chronic kidney disease. [electronic resource] - Journal of the American Society of Nephrology : JASN Jun 2011 - 1064-75 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural

1533-3450

10.1681/ASN.2010090956 doi


Actins--metabolism
Animals
Antineoplastic Agents--pharmacology
Cells, Cultured
Chronic Disease
Disease Models, Animal
Disease Progression
Fibroblasts--cytology
Fibronectins--metabolism
Fibrosis
Kidney--drug effects
Kidney Diseases--drug therapy
Male
Mice
Mice, Inbred C57BL
Proteinuria--prevention & control
Rats
Rats, Sprague-Dawley
Smad Proteins--metabolism
Suramin--pharmacology
Transforming Growth Factor beta1--metabolism
Treatment Outcome