Discovery and characterization of a nonphosphorylated cyclic peptide inhibitor of the peptidylprolyl isomerase, Pin1.

Duncan, Kelly E

Discovery and characterization of a nonphosphorylated cyclic peptide inhibitor of the peptidylprolyl isomerase, Pin1. [electronic resource] - Journal of medicinal chemistry Jun 2011 - 3854-65 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1520-4804

10.1021/jm200156c doi


Binding Sites
Catalytic Domain
Drug Discovery
Enzyme Inhibitors--chemical synthesis
Molecular Structure
Molecular Targeted Therapy
NIMA-Interacting Peptidylprolyl Isomerase
Peptide Library
Peptides, Cyclic--chemical synthesis
Peptidylprolyl Isomerase--antagonists & inhibitors
Phosphorylation
Protein Binding
Protein Conformation
Substrate Specificity