Alginate oligosaccharide protects against endoplasmic reticulum- and mitochondrial-mediated apoptotic cell death and oxidative stress.

Tusi, Solaleh Khoramian

Alginate oligosaccharide protects against endoplasmic reticulum- and mitochondrial-mediated apoptotic cell death and oxidative stress. [electronic resource] - Biomaterials Aug 2011 - 5438-58 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1878-5905

10.1016/j.biomaterials.2011.04.024 doi


Alginates--chemistry
Amyloid beta-Peptides--pharmacology
Animals
Apoptosis--drug effects
Apoptosis Inducing Factor--metabolism
Calcium--metabolism
Caspase 12--metabolism
Caspase 3--metabolism
Cell Nucleus--drug effects
Cell Shape--drug effects
Cell Survival--drug effects
Cytochromes c--metabolism
Endoplasmic Reticulum--drug effects
Extracellular Signal-Regulated MAP Kinases--metabolism
Glucuronic Acid--chemistry
Glutathione--metabolism
HSP70 Heat-Shock Proteins--metabolism
HSP90 Heat-Shock Proteins--metabolism
Hexuronic Acids--chemistry
Hydrogen Peroxide--pharmacology
Mitochondria--drug effects
Models, Biological
NF-E2-Related Factor 2--metabolism
NF-kappa B--metabolism
Neurons--cytology
Oligosaccharides--pharmacology
Oxidation-Reduction--drug effects
Oxidative Stress--drug effects
PC12 Cells
Peptide Fragments--pharmacology
Phosphorylation--drug effects
Poly(ADP-ribose) Polymerases--metabolism
Polysaccharide-Lyases--chemistry
Proto-Oncogene Proteins c-bcl-2--metabolism
Rats
Reactive Oxygen Species--metabolism
Tumor Suppressor Protein p53--metabolism
bcl-2-Associated X Protein--metabolism