The encephalitogenicity of T(H)17 cells is dependent on IL-1- and IL-23-induced production of the cytokine GM-CSF.
El-Behi, Mohamed
The encephalitogenicity of T(H)17 cells is dependent on IL-1- and IL-23-induced production of the cytokine GM-CSF. [electronic resource] - Nature immunology Jun 2011 - 568-75 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural
1529-2916
10.1038/ni.2031 doi
Animals
Antibodies--immunology
CD11c Antigen--immunology
CD4-Positive T-Lymphocytes--drug effects
Cells, Cultured
Coculture Techniques
Encephalomyelitis, Autoimmune, Experimental--chemically induced
Female
Flow Cytometry
Glycoproteins
Granulocyte-Macrophage Colony-Stimulating Factor--genetics
Interleukin-1--pharmacology
Interleukin-1beta--pharmacology
Interleukin-23--immunology
Mice
Mice, Inbred C57BL
Mice, Knockout
Mice, Transgenic
Myelin-Oligodendrocyte Glycoprotein
Nuclear Receptor Subfamily 1, Group F, Member 3--genetics
Peptide Fragments
Th1 Cells--drug effects
Th17 Cells--drug effects
Transforming Growth Factor beta--pharmacology
The encephalitogenicity of T(H)17 cells is dependent on IL-1- and IL-23-induced production of the cytokine GM-CSF. [electronic resource] - Nature immunology Jun 2011 - 568-75 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural
1529-2916
10.1038/ni.2031 doi
Animals
Antibodies--immunology
CD11c Antigen--immunology
CD4-Positive T-Lymphocytes--drug effects
Cells, Cultured
Coculture Techniques
Encephalomyelitis, Autoimmune, Experimental--chemically induced
Female
Flow Cytometry
Glycoproteins
Granulocyte-Macrophage Colony-Stimulating Factor--genetics
Interleukin-1--pharmacology
Interleukin-1beta--pharmacology
Interleukin-23--immunology
Mice
Mice, Inbred C57BL
Mice, Knockout
Mice, Transgenic
Myelin-Oligodendrocyte Glycoprotein
Nuclear Receptor Subfamily 1, Group F, Member 3--genetics
Peptide Fragments
Th1 Cells--drug effects
Th17 Cells--drug effects
Transforming Growth Factor beta--pharmacology