Mitragynine inhibits the COX-2 mRNA expression and prostaglandin E₂ production induced by lipopolysaccharide in RAW264.7 macrophage cells.

Utar, Zulkhurnain

Mitragynine inhibits the COX-2 mRNA expression and prostaglandin E₂ production induced by lipopolysaccharide in RAW264.7 macrophage cells. [electronic resource] - Journal of ethnopharmacology Jun 2011 - 75-82 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1872-7573

10.1016/j.jep.2011.04.011 doi


Animals
Anti-Inflammatory Agents--pharmacology
Cell Line
Cyclooxygenase 1--genetics
Cyclooxygenase 2--genetics
Cyclooxygenase 2 Inhibitors--pharmacology
Dinoprostone--antagonists & inhibitors
Dose-Response Relationship, Drug
Lipopolysaccharides
Macrophages--drug effects
Mice
Mitragyna--chemistry
Plant Extracts--pharmacology
RNA, Messenger--metabolism
Secologanin Tryptamine Alkaloids--pharmacology