Pre-clinical evaluation of three non-viral gene transfer agents for cystic fibrosis after aerosol delivery to the ovine lung.

McLachlan, G

Pre-clinical evaluation of three non-viral gene transfer agents for cystic fibrosis after aerosol delivery to the ovine lung. [electronic resource] - Gene therapy Oct 2011 - 996-1005 p. digital

Publication Type: Comparative Study; Evaluation Study; Journal Article; Research Support, Non-U.S. Gov't

1476-5462

10.1038/gt.2011.55 doi


Administration, Inhalation
Animals
Cystic Fibrosis--genetics
Cystic Fibrosis Transmembrane Conductance Regulator--genetics
DNA, Complementary--administration & dosage
Gene Transfer Techniques
Genetic Therapy--methods
Humans
Liposomes--administration & dosage
Nanoparticles--administration & dosage
Polyethylene Glycols
Polyethyleneimine--administration & dosage
RNA, Messenger--metabolism
Sheep