LiCl attenuates thapsigargin-induced tau hyperphosphorylation by inhibiting GSK-3β in vivo and in vitro.

Fu, Zheng-Qi

LiCl attenuates thapsigargin-induced tau hyperphosphorylation by inhibiting GSK-3β in vivo and in vitro. [electronic resource] - Journal of Alzheimer's disease : JAD 2010 - 1107-17 p. digital

Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't

1875-8908

10.3233/jad-2010-100687 doi


Animals
Cell Line, Tumor
Coculture Techniques
Glycogen Synthase Kinase 3--antagonists & inhibitors
Glycogen Synthase Kinase 3 beta
HEK293 Cells
Humans
Lithium Chloride--pharmacology
Male
Phosphorylation--drug effects
Protein Kinase Inhibitors--pharmacology
Rats
Rats, Sprague-Dawley
Thapsigargin--antagonists & inhibitors
tau Proteins--metabolism