B cells promote insulin resistance through modulation of T cells and production of pathogenic IgG antibodies.

Winer, Daniel A

B cells promote insulin resistance through modulation of T cells and production of pathogenic IgG antibodies. [electronic resource] - Nature medicine May 2011 - 610-7 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1546-170X

10.1038/nm.2353 doi


Animals
Autoantibodies--biosynthesis
Autoantigens--immunology
Autoimmunity
B-Lymphocytes--immunology
Dietary Fats--adverse effects
Glucose--metabolism
Humans
Immunoglobulin G--biosynthesis
Immunoglobulin mu-Chains--genetics
Inflammation--immunology
Insulin Resistance--immunology
Intra-Abdominal Fat--immunology
Lymphocyte Activation
Lymphocyte Depletion
Male
Mice
Mice, Inbred C57BL
Mice, Knockout
Obesity--etiology
T-Lymphocytes--immunology