Molecular modeling and molecular dynamics simulation studies of the GSK3β/ATP/substrate complex: understanding the unique P+4 primed phosphorylation specificity for GSK3β substrates.

Lu, Shao-Yong

Molecular modeling and molecular dynamics simulation studies of the GSK3β/ATP/substrate complex: understanding the unique P+4 primed phosphorylation specificity for GSK3β substrates. [electronic resource] - Journal of chemical information and modeling May 2011 - 1025-36 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1549-960X

10.1021/ci100493j doi


Adenosine Triphosphate--chemistry
Amino Acid Motifs
Catalytic Domain
Glycogen Synthase--chemistry
Glycogen Synthase Kinase 3--chemistry
Glycogen Synthase Kinase 3 beta
Humans
Kinetics
Molecular Dynamics Simulation
Phosphorylation
Protein Binding
Protein Structure, Secondary
Serine--chemistry
Substrate Specificity
Thermodynamics