Nonsense suppressor therapies rescue peroxisome lipid metabolism and assembly in cells from patients with specific PEX gene mutations.

Dranchak, Patricia K

Nonsense suppressor therapies rescue peroxisome lipid metabolism and assembly in cells from patients with specific PEX gene mutations. [electronic resource] - Journal of cellular biochemistry May 2011 - 1250-8 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural

1097-4644

10.1002/jcb.22979 doi


Alleles
Animals
CHO Cells
Chondrodysplasia Punctata, Rhizomelic--metabolism
Codon, Nonsense--drug effects
Cricetinae
Cricetulus
Female
Fibroblasts--metabolism
Gentamicins--therapeutic use
Humans
Lipid Metabolism--genetics
Membrane Proteins--genetics
Oxadiazoles--therapeutic use
Peroxisomal Biogenesis Factor 2
Peroxisomal Disorders--drug therapy
Peroxisomal Targeting Signal 2 Receptor
Plasmalogens--genetics
Receptors, Cytoplasmic and Nuclear--metabolism