Microwave-assisted synthesis, crystal structure of pyrazolo[1,5-a]pyrazin-4(5H)-ones and their selective effects on lung cancer cells.

Liu, Ning

Microwave-assisted synthesis, crystal structure of pyrazolo[1,5-a]pyrazin-4(5H)-ones and their selective effects on lung cancer cells. [electronic resource] - European journal of medicinal chemistry Jun 2011 - 2359-67 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1768-3254

10.1016/j.ejmech.2011.03.018 doi


Antineoplastic Agents--chemical synthesis
Apoptosis--drug effects
Cell Cycle--drug effects
Cell Proliferation--drug effects
Cell Survival--drug effects
Crystallography, X-Ray
Dose-Response Relationship, Drug
Drug Screening Assays, Antitumor
Humans
Lung Neoplasms--drug therapy
Microwaves
Models, Molecular
Molecular Structure
Pyrazines--chemical synthesis
Pyrazoles--chemical synthesis
Stereoisomerism
Structure-Activity Relationship
Tumor Cells, Cultured