Mechanism of kinase inactivation and nonbinding of FRATide to GSK3β due to K85M mutation: molecular dynamics simulation and normal mode analysis.
Lu, Shaoyong
Mechanism of kinase inactivation and nonbinding of FRATide to GSK3β due to K85M mutation: molecular dynamics simulation and normal mode analysis. [electronic resource] - Biopolymers Oct 2011 - 669-81 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
0006-3525
10.1002/bip.21629 doi
Adenosine Triphosphate--metabolism
Amino Acid Substitution
Animals
Catalytic Domain--genetics
Crystallography, X-Ray
Glycogen Synthase Kinase 3--antagonists & inhibitors
Glycogen Synthase Kinase 3 beta
Models, Molecular
Molecular Dynamics Simulation
Mutagenesis, Site-Directed
Protein Binding
Protein Conformation
Mechanism of kinase inactivation and nonbinding of FRATide to GSK3β due to K85M mutation: molecular dynamics simulation and normal mode analysis. [electronic resource] - Biopolymers Oct 2011 - 669-81 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
0006-3525
10.1002/bip.21629 doi
Adenosine Triphosphate--metabolism
Amino Acid Substitution
Animals
Catalytic Domain--genetics
Crystallography, X-Ray
Glycogen Synthase Kinase 3--antagonists & inhibitors
Glycogen Synthase Kinase 3 beta
Models, Molecular
Molecular Dynamics Simulation
Mutagenesis, Site-Directed
Protein Binding
Protein Conformation