Contribution of SPECT measurements of D2 and 5-HT2A occupancy to the clinical development of the antipsychotic SB-773812.
Catafau, Ana M
Contribution of SPECT measurements of D2 and 5-HT2A occupancy to the clinical development of the antipsychotic SB-773812. [electronic resource] - Journal of nuclear medicine : official publication, Society of Nuclear Medicine Apr 2011 - 526-34 p. digital
Publication Type: Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
1535-5667
10.2967/jnumed.110.081885 doi
Adult
Algorithms
Antipsychotic Agents--pharmacokinetics
Brain--diagnostic imaging
Cohort Studies
Diagnostic and Statistical Manual of Mental Disorders
Dose-Response Relationship, Drug
Humans
Image Processing, Computer-Assisted
Iodobenzenes
Male
Piperidines
Radiopharmaceuticals
Receptor, Serotonin, 5-HT2A--metabolism
Receptors, Dopamine D2--metabolism
Risperidone--pharmacokinetics
Schizophrenia--metabolism
Tomography, Emission-Computed, Single-Photon--methods
Young Adult
Contribution of SPECT measurements of D2 and 5-HT2A occupancy to the clinical development of the antipsychotic SB-773812. [electronic resource] - Journal of nuclear medicine : official publication, Society of Nuclear Medicine Apr 2011 - 526-34 p. digital
Publication Type: Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
1535-5667
10.2967/jnumed.110.081885 doi
Adult
Algorithms
Antipsychotic Agents--pharmacokinetics
Brain--diagnostic imaging
Cohort Studies
Diagnostic and Statistical Manual of Mental Disorders
Dose-Response Relationship, Drug
Humans
Image Processing, Computer-Assisted
Iodobenzenes
Male
Piperidines
Radiopharmaceuticals
Receptor, Serotonin, 5-HT2A--metabolism
Receptors, Dopamine D2--metabolism
Risperidone--pharmacokinetics
Schizophrenia--metabolism
Tomography, Emission-Computed, Single-Photon--methods
Young Adult