Phosphodiesterase-5A (PDE5A) is localized to the endothelial caveolae and modulates NOS3 activity.

Gebska, Milena A

Phosphodiesterase-5A (PDE5A) is localized to the endothelial caveolae and modulates NOS3 activity. [electronic resource] - Cardiovascular research May 2011 - 353-63 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1755-3245

10.1093/cvr/cvq410 doi


Animals
Aorta--cytology
Cattle
Caveolae--metabolism
Cells, Cultured
Coronary Vessels--cytology
Cyclic GMP-Dependent Protein Kinase Type I
Cyclic GMP-Dependent Protein Kinases--genetics
Cyclic Nucleotide Phosphodiesterases, Type 5--genetics
Endothelial Cells--cytology
Humans
Hypertension, Pulmonary--metabolism
Membrane Microdomains--metabolism
Mice
Nitric Oxide Synthase Type III--metabolism
Pulmonary Artery--cytology
Signal Transduction--physiology
Umbilical Veins--cytology
Vasodilation--physiology