Leptin enhances NMDA-induced spinal excitation in rats: A functional link between adipocytokine and neuropathic pain.

Tian, Yinghong

Leptin enhances NMDA-induced spinal excitation in rats: A functional link between adipocytokine and neuropathic pain. [electronic resource] - Pain Jun 2011 - 1263-1271 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural

1872-6623

10.1016/j.pain.2011.01.054 doi


Analysis of Variance
Animals
Behavior, Animal--drug effects
Dizocilpine Maleate--therapeutic use
Drug Interactions
Electric Stimulation--methods
Excitatory Amino Acid Agonists--pharmacology
Excitatory Amino Acid Antagonists--therapeutic use
Hyperalgesia--drug therapy
In Vitro Techniques
Leptin--pharmacology
Male
Membrane Potentials--drug effects
Mice
Mice, Knockout
N-Methylaspartate--pharmacology
Neuralgia--chemically induced
Pain Measurement
Patch-Clamp Techniques--methods
Physical Stimulation--adverse effects
Rats
Rats, Sprague-Dawley
Receptors, Leptin--deficiency
Receptors, N-Methyl-D-Aspartate--metabolism
STAT3 Transcription Factor--metabolism
Sensory Receptor Cells--drug effects
Signal Transduction--drug effects
Spinal Cord--cytology
Up-Regulation--drug effects